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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KALRN All Species: 22.42
Human Site: S2516 Identified Species: 54.81
UniProt: O60229 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60229 NP_003938.1 2985 340174 S2516 N I L D T D N S S A T Y T V S
Chimpanzee Pan troglodytes XP_516703 2991 340419 S2522 N I L D T D N S S A T Y T V S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535768 3009 341980 S2540 N I L D T D N S S A T Y T V S
Cat Felis silvestris
Mouse Mus musculus A2CG49 2964 336982 S2489 N I L D T D N S S A T Y T I S
Rat Rattus norvegicus P97924 2959 336568 S2490 N I L D T D N S S A T Y T I S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519275 3047 344048 P2572 S A V I I D N P D G T I K K S
Chicken Gallus gallus XP_001234055 3038 345602 S2569 N I L D N D N S T A T Y T V S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LUA6 3028 342343 W2534 Q C P A A E G W I P G Y V L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651960 2263 256958 A1856 I Q E P H L I A N G P P A F A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783478 2887 322988 P2436 Q V C G R P R P M I T W R D P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 N.A. 97.4 N.A. 97 97 N.A. 61.7 91.8 N.A. 60.9 N.A. 34 N.A. N.A. 21.2
Protein Similarity: 100 98.8 N.A. 98.3 N.A. 98.3 98.3 N.A. 76.4 95.2 N.A. 75.3 N.A. 50.8 N.A. N.A. 39.9
P-Site Identity: 100 100 N.A. 100 N.A. 93.3 93.3 N.A. 26.6 86.6 N.A. 6.6 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 40 93.3 N.A. 20 N.A. 20 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 10 0 0 10 0 60 0 0 10 0 10 % A
% Cys: 0 10 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 60 0 70 0 0 10 0 0 0 0 10 0 % D
% Glu: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 0 0 0 10 0 0 10 0 0 20 10 0 0 0 10 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 60 0 10 10 0 10 0 10 10 0 10 0 20 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % K
% Leu: 0 0 60 0 0 10 0 0 0 0 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 60 0 0 0 10 0 70 0 10 0 0 0 0 0 0 % N
% Pro: 0 0 10 10 0 10 0 20 0 10 10 10 0 0 10 % P
% Gln: 20 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 10 0 10 0 0 0 0 0 10 0 0 % R
% Ser: 10 0 0 0 0 0 0 60 50 0 0 0 0 0 70 % S
% Thr: 0 0 0 0 50 0 0 0 10 0 80 0 60 0 0 % T
% Val: 0 10 10 0 0 0 0 0 0 0 0 0 10 40 0 % V
% Trp: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 70 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _